Title : Synthesis of New Tricyclic and Tetracyclic Fused Coumarin Sulfonate Derivatives and Their Inhibitory Effects on LPS-Induced Nitric Oxide and PGE2 Productions in RAW 264.7 Macrophages: Part 2.

Pub. Date : 2016 Nov

PMID : 27779319






1 Functional Relationships(s)
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1 Their IC50 values against the COX-2 enzyme were 0.67 and 0.85 microM, respectively, which is more potent than etoricoxib. Etoricoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens