Pub. Date : 2016 Oct 24
PMID : 27775054
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Thromboxane A2 receptor antagonist SQ29548 reduces ischemic stroke-induced microglia/macrophages activation and enrichment, and ameliorates brain injury. | SQ 29548 | thromboxane A2 receptor | Mus musculus |
| 2 | We have previously shown that TXA2R antagonist SQ29548 attenuates BV2 microglia activation by suppression of ERK pathway, but its effect is not tested in vivo. | SQ 29548 | thromboxane A2 receptor | Mus musculus |
| 3 | TXA2R antagonist SQ29548 inhibited ischemia-induced inflammatory response and furthermore reduced microglia/macrophages activation and ischemic/reperfusion brain injury. | SQ 29548 | thromboxane A2 receptor | Mus musculus |