Title : Allosteric regulation by cooperative conformational changes of actin filaments drives mutually exclusive binding with cofilin and myosin.

Pub. Date : 2016 Oct 20

PMID : 27762277






2 Functional Relationships(s)
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Protein Name
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1 Fluorescence microscopy demonstrated that HMM-GFP and cofilin-mCherry each bound cooperatively to different parts of actin filaments when they were added simultaneously in 0.2 muM ATP, indicating that the two cooperative bindings are mutually exclusive. Adenosine Triphosphate cofilin 1 Homo sapiens
2 In 0.1 mM ATP, the motor domain of myosin (S1) strongly inhibited the formation of cofilin clusters along actin filaments. Adenosine Triphosphate cofilin 1 Homo sapiens