Pub. Date : 2016 Dec 1
PMID : 27760762
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Endothelin-1-Rho kinase interactions impair lung structure and cause pulmonary hypertension after bleomycin exposure in neonatal rat pups. | Bleomycin | endothelin 1 | Rattus norvegicus |
2 | Bleomycin increased lung ET-1 protein expression by 65%, RV/LV+S by 60%, mean linear intercept (MLI) by 212%, and MWT by 140% and decreased radial alveolar count (RAC) and vessel density by 40 and 44%, respectively (P < 0.01 for each comparison). | Bleomycin | endothelin 1 | Rattus norvegicus |