Title : Endothelin-1-Rho kinase interactions impair lung structure and cause pulmonary hypertension after bleomycin exposure in neonatal rat pups.

Pub. Date : 2016 Dec 1

PMID : 27760762






2 Functional Relationships(s)
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Protein Name
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1 Endothelin-1-Rho kinase interactions impair lung structure and cause pulmonary hypertension after bleomycin exposure in neonatal rat pups. Bleomycin endothelin 1 Rattus norvegicus
2 Bleomycin increased lung ET-1 protein expression by 65%, RV/LV+S by 60%, mean linear intercept (MLI) by 212%, and MWT by 140% and decreased radial alveolar count (RAC) and vessel density by 40 and 44%, respectively (P < 0.01 for each comparison). Bleomycin endothelin 1 Rattus norvegicus