Title : Farnesoid X Receptor and Its Ligands Inhibit the Function of Platelets.

Pub. Date : 2016 Dec

PMID : 27758768






3 Functional Relationships(s)
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1 In this study, we show that FXR is present in human platelets and FXR ligands, GW4064 and 6alpha-ethyl-chenodeoxycholic acid, modulate platelet activation nongenomically. GW 4064 nuclear receptor subfamily 1 group H member 4 Homo sapiens
2 In this study, we show that FXR is present in human platelets and FXR ligands, GW4064 and 6alpha-ethyl-chenodeoxycholic acid, modulate platelet activation nongenomically. GW 4064 nuclear receptor subfamily 1 group H member 4 Homo sapiens
3 The atheroprotective effects of GW4064, with its novel antiplatelet effects, indicate FXR as a potential target for the prevention of atherothrombotic disease. GW 4064 nuclear receptor subfamily 1 group H member 4 Homo sapiens