Title : Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract.

Pub. Date : 2016 Oct 18

PMID : 27751235






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract. polyglutamine huntingtin Rattus norvegicus
2 In Huntington"s disease (HD), neurotoxicity correlates with an increased aggregation propensity of a polyglutamine (polyQ) expansion in exon 1 of mutant huntingtin protein (mHtt). polyglutamine huntingtin Rattus norvegicus
3 In Huntington"s disease (HD), neurotoxicity correlates with an increased aggregation propensity of a polyglutamine (polyQ) expansion in exon 1 of mutant huntingtin protein (mHtt). polyglutamine huntingtin Rattus norvegicus