Title : Frontline Science: D1 dopaminergic receptor signaling activates the AMPK-bioenergetic pathway in macrophages and alveolar epithelial cells and reduces endotoxin-induced ALI.

Pub. Date : 2017 Feb

PMID : 27733575






1 Functional Relationships(s)
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1 Furthermore, we show that a culture of AECs with either fenoldopam or the AMPK activator metformin effectively diminished IL-1beta-induced release of adverse paracrine signaling, which promotes the macrophage proinflammatory response. Metformin interleukin 1 beta Mus musculus