Title : Hydrogen peroxide triggers a novel alternative splicing of arsenic (+3 oxidation state) methyltransferase gene.

Pub. Date : 2016 Nov 4

PMID : 27721063






1 Functional Relationships(s)
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1 We previously reported that two splicing variants of human AS3MT mRNA, exon-3 skipping form (Delta3) and exons-4 and -5 skipping form (Delta4,5), were detected in HepG2 cells and that both variants lacked arsenic methylation activity (Sumi et al., 2011). Arsenic arsenite methyltransferase Homo sapiens