Title : CysLT1R downregulation reverses intracerebroventricular streptozotocin-induced memory impairment via modulation of neuroinflammation in mice.

Pub. Date : 2017 Feb 6

PMID : 27720931






2 Functional Relationships(s)
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1 Our previous studies showed that cysteinyl leukotrienes receptor 1 (CysLT1R) is upregulated in amyloid-beta (Abeta)-induced neurotoxicity and that administration of CysLT1R antagonists such as pranlukast or montelukast can ameliorate memory impairment in mice. pranlukast cysteinyl leukotriene receptor 1 Mus musculus
2 Our previous studies showed that cysteinyl leukotrienes receptor 1 (CysLT1R) is upregulated in amyloid-beta (Abeta)-induced neurotoxicity and that administration of CysLT1R antagonists such as pranlukast or montelukast can ameliorate memory impairment in mice. pranlukast cysteinyl leukotriene receptor 1 Mus musculus