Pub. Date : 2016 Sep 14
PMID : 27720690
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Aluminum trichloride induces bone impairment through TGF-beta1/Smad signaling pathway. | Aluminum Chloride | SMAD family member 4 | Rattus norvegicus |
| 2 | Moreover, we found exogenous TGF-beta1 application reversed the inhibitory effect of AlCl3 on osteoblasts activity by activating the TGF-beta1/Smad signaling pathway and increasing the mRNA expressions of ALP and Col I in osteoblasts. | Aluminum Chloride | SMAD family member 4 | Rattus norvegicus |
| 3 | These results demonstrate that AlCl3 induces bone impairment through inactivation of TGF-beta1/Smad signaling pathway. | Aluminum Chloride | SMAD family member 4 | Rattus norvegicus |