Title : Update on the Genetic Polymorphisms of Drug-Metabolizing Enzymes in Antiepileptic Drug Therapy.

Pub. Date : 2010 Aug 20

PMID : 27713373






1 Functional Relationships(s)
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1 The defective alleles of CYP2C9 and/or CYP2C19 were also found to have clinically significant effects on the inter-individual variabilities in the population pharmacokinetics of phenobarbital, valproic acid and zonisamide. Phenobarbital cytochrome P450 family 2 subfamily C member 19 Homo sapiens