Pub. Date : 2009 Dec 15
PMID : 27713232
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The [14C]Gly-Sar uptake via PEPT1 was inhibited by Zn2+ and Cu2+ treatment in a concentration-dependent manner (Ki values 107 +- 23 and 19 +- 5 muM, respectively). | Glycine | solute carrier family 15 member 1 | Homo sapiens |
| 2 | Kinetic analysis showed that the Kt of Gly-Sar uptake was increased 2-fold in the presence of zinc sulphate (150 muM) whereas the Vmax value were not affected suggesting that zinc ions inhibited Gly-Sar uptake by PEPT1 in a competitively manner. | Glycine | solute carrier family 15 member 1 | Homo sapiens |