Pub. Date : 2017 Mar
PMID : 27704398
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Genetic testing revealed the presence of a heterozygous variant of unknown significance (VUS) in the cysteine-rich region of exon 10 in the RET gene (c.1846G>C, p.E616Q), in both affected siblings and their unaffected mother. | Cysteine | ret proto-oncogene | Homo sapiens |
2 | Variants in the cysteine-rich region of the RET gene, outside of the key cysteine residues, may contribute to the development of MEN2 in a less aggressive manner, with a lower penetrance of MTC. | Cysteine | ret proto-oncogene | Homo sapiens |
3 | Variants in the cysteine-rich region of the RET gene, outside of the key cysteine residues, may contribute to the development of MEN2 in a less aggressive manner, with a lower penetrance of MTC. | Cysteine | ret proto-oncogene | Homo sapiens |