Title : Analysis of the add-on effect of α-glucosidase inhibitor, acarbose in insulin therapy: A pilot study.

Pub. Date : 2016 Oct

PMID : 27699014






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1 Analysis of the add-on effect of alpha-glucosidase inhibitor, acarbose in insulin therapy: A pilot study. Acarbose insulin Homo sapiens
2 The aim of the present study was to evaluate the add-on effect of acarbose therapy in oxidative stress, and the lipid and inflammatory profiles of patients with type 2 diabetes mellitus (T2DM) treated with insulin. Acarbose insulin Homo sapiens
3 Patients that received acarbose plus insulin demonstrated greater reduction in 8-iso PGF2alpha, Hs-CRP, TNF-alpha, IL-1beta and IL-6 levels when compared with the insulin only patients. Acarbose insulin Homo sapiens
4 Thus, acarbose add-on insulin therapy was identified to be associated with greater improvements in oxidative stress and inflammation in patients with T2DM when compared with those that received insulin only therapy. Acarbose insulin Homo sapiens