Pub. Date : 2016 Oct
PMID : 27697512
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DHCR7: A vital enzyme switch between cholesterol and vitamin D production. | Vitamin D | 7-dehydrocholesterol reductase | Homo sapiens |
| 2 | Besides serving as a substrate for DHCR7, 7-dehydrocholesterol is also a precursor of vitamin D via the action of ultraviolet light on the skin. | Vitamin D | 7-dehydrocholesterol reductase | Homo sapiens |
| 3 | Thus, DHCR7 exerts complex biological effects, involved in both cholesterol and vitamin D production. | Vitamin D | 7-dehydrocholesterol reductase | Homo sapiens |
| 4 | Indeed, we argue that DHCR7 can act as a switch between cholesterol and vitamin D synthesis. | Vitamin D | 7-dehydrocholesterol reductase | Homo sapiens |
| 5 | This review summarizes current knowledge about the critical enzyme DHCR7, highlighting recent findings regarding its structure, transcriptional and post-transcriptional regulation, and its links to vitamin D synthesis. | Vitamin D | 7-dehydrocholesterol reductase | Homo sapiens |