Title : Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases.

Pub. Date : 2017 Sep 10

PMID : 27692933






1 Functional Relationships(s)
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1 Incubations of HLM with phase I and phase II drug probes showed that oxycodone mainly decreased the in vitro activities of CYP2D6, CYP3A4/5, UGT1A3, UGT1A6 and UGT2B subfamily with an important impact on UGT2B7. Oxycodone cytochrome P450 family 2 subfamily D member 6 Homo sapiens