Title : Immunomodulatory effects of nicotine on interleukin 1β activated human astrocytes and the role of cyclooxygenase 2 in the underlying mechanism.

Pub. Date : 2016 Sep 29

PMID : 27681882






2 Functional Relationships(s)
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1 For the COX-2 inhibition studies, enzyme activity was inhibited using NS-398. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide prostaglandin-endoperoxide synthase 2 Homo sapiens
2 Importantly, nicotine"s inhibitory effect on IL-6 production was reversed with the specific COX-2 inhibitor NS-398. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide prostaglandin-endoperoxide synthase 2 Homo sapiens