Title : Immunochemical characterization of cytochrome P-450 isozymes responsible for benzene oxidation in the rat liver.

Pub. Date : 1989 Sep

PMID : 2766463






4 Functional Relationships(s)
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1 These results indicate that (i) cytochromes P-450b,e and P-450j contribute to benzene metabolism in rat liver; (ii) the former has a low affinity to benzene and is induced by PB; and (iii) P-450j has a high affinity to benzene and is induced by 1-day fasting, pyrazole and ethanol, but decreased by PB treatment. Phenobarbital cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus
2 These results indicate that (i) cytochromes P-450b,e and P-450j contribute to benzene metabolism in rat liver; (ii) the former has a low affinity to benzene and is induced by PB; and (iii) P-450j has a high affinity to benzene and is induced by 1-day fasting, pyrazole and ethanol, but decreased by PB treatment. Phenobarbital cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus
3 These results indicate that (i) cytochromes P-450b,e and P-450j contribute to benzene metabolism in rat liver; (ii) the former has a low affinity to benzene and is induced by PB; and (iii) P-450j has a high affinity to benzene and is induced by 1-day fasting, pyrazole and ethanol, but decreased by PB treatment. Phenobarbital cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus
4 These results indicate that (i) cytochromes P-450b,e and P-450j contribute to benzene metabolism in rat liver; (ii) the former has a low affinity to benzene and is induced by PB; and (iii) P-450j has a high affinity to benzene and is induced by 1-day fasting, pyrazole and ethanol, but decreased by PB treatment. Phenobarbital cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus