Title : Expression of a human multidrug resistance gene in ovarian carcinomas.

Pub. Date : 1989 Sep 15

PMID : 2766278






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 MDR1 transcripts (4.5 kilobases) were observed in the RNA preparations obtained from 3 of 10 patients who were treated with doxorubicin or vincristine, 2 drugs known to select the MDR phenotype in vitro. Doxorubicin ATP binding cassette subfamily B member 1 Homo sapiens
2 Our study suggests that, in spite of the weak occurrence of the MDR process in patients with ovarian cancers, MDR1 expression can be related to previous treatment with doxorubicin or vincristine. Doxorubicin ATP binding cassette subfamily B member 1 Homo sapiens