Pub. Date : 2016 Sep 20
PMID : 27653678
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | IFN-gamma Induces Histone 3 Lysine 27 Trimethylation in a Small Subset of Promoters to Stably Silence Gene Expression in Human Macrophages. | Lysine | interferon gamma | Homo sapiens |
| 2 | By using transcriptomic and epigenomic analysis, we found that stable repression of a small group of genes by IFN-gamma is associated with recruitment of the histone methyltransferase EZH2 and deposition of the negative mark histone 3 lysine 27 trimethylation (H3K27me3) at their promoters. | Lysine | interferon gamma | Homo sapiens |