Title : The effect of adenosine A1 receptor agonist and antagonist on p53 and caspase 3, 8, and 9 expression and apoptosis rate in MCF-7 breast cancer cell line.

Pub. Date : 2016 Jul

PMID : 27651810






2 Functional Relationships(s)
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1 Our findings indicated that DPCPX significantly induced apoptosis in MCF-7 cells while the cell viability was reduced specially 72 h after the treatment and the expression of p53 gene and caspase expressions was dramatically up-regulated. 1,3-dipropyl-8-cyclopentylxanthine tumor protein p53 Homo sapiens
2 Furthermore, DPCPX induced p53 and caspase 3, 8 and 9 expressions that consequently promotes the cell apoptosis in MCF-7 cells. 1,3-dipropyl-8-cyclopentylxanthine tumor protein p53 Homo sapiens