Title : Oxidized Low-Density Lipoprotein (OxLDL)-Treated Dendritic Cells Promote Activation of T Cells in Human Atherosclerotic Plaque and Blood, Which Is Repressed by Statins: microRNA let-7c Is Integral to the Effect.

Pub. Date : 2016 Sep 20

PMID : 27650878






1 Functional Relationships(s)
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1 Atorvastatin and simvastatin suppressed the DC maturation showing lower expression of CD80, CD83, and CD86, and limited their production of tumor necrosis factor-alpha, IL-1beta and IL-6, and increased transforming growth factor-beta and IL-10 secretion. Simvastatin interleukin 6 Homo sapiens