Title : The NADPH Oxidases DUOX1 and NOX2 Play Distinct Roles in Redox Regulation of Epidermal Growth Factor Receptor Signaling.

Pub. Date : 2016 Oct 28

PMID : 27650496






2 Functional Relationships(s)
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1 Moreover, the intrinsic kinase activity of recombinant Src or EGFR was in both cases enhanced by H2O2 but not by GSSG, indicating that the intermediate sulfenylation is the activating modification. Hydrogen Peroxide epidermal growth factor receptor Homo sapiens
2 H2O2-induced increase in EGFR tyrosine kinase activity was not observed with the C797S variant, confirming Cys-797 as the redox-sensitive cysteine residue that regulates kinase activity. Hydrogen Peroxide epidermal growth factor receptor Homo sapiens