Title : Antiviral Nucleotide Incorporation by Recombinant Human Mitochondrial RNA Polymerase Is Predictive of Increased In Vivo Mitochondrial Toxicity Risk.

Pub. Date : 2016 Dec

PMID : 27645237






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The active triphosphate metabolite of compound 1, compound 2, does not inhibit human alpha, beta, or gamma DNA polymerases but was a substrate for incorporation by the human mitochondrial RNA polymerase (POLRMT). triphosphoric acid RNA polymerase mitochondrial Homo sapiens