Title : The association of ACE gene polymorphism with diabetic kidney disease and renoprotective efficacy of valsartan.

Pub. Date : 2016 Jul

PMID : 27638852






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1 The association of ACE gene polymorphism with diabetic kidney disease and renoprotective efficacy of valsartan. Valsartan angiotensin I converting enzyme Homo sapiens
2 INTRODUCTION: To investigate the associations between the insertion/deletion (I/D) polymorphisms in the angiotensin converting enzyme (ACE) gene and susceptibility to diabetic kidney disease (DKD); and the efficacy of valsartan in reducing the urine protein in Type 2 diabetes mellitus (T2DM) patients. Valsartan angiotensin I converting enzyme Homo sapiens
3 INTRODUCTION: To investigate the associations between the insertion/deletion (I/D) polymorphisms in the angiotensin converting enzyme (ACE) gene and susceptibility to diabetic kidney disease (DKD); and the efficacy of valsartan in reducing the urine protein in Type 2 diabetes mellitus (T2DM) patients. Valsartan angiotensin I converting enzyme Homo sapiens
4 Furthermore, the ACE I/D polymorphism influenced the renoprotective response to valsartan: Patients with the DD genotype benefitted the most from this treatment. Valsartan angiotensin I converting enzyme Homo sapiens