Pub. Date : 2016 Sep 14
PMID : 27624652
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Following thromboembolic stroke bexarotene enhanced autophagy in the ischemic brain concomitantly with a reduction in lesion volume and amelioration of behavioral deficits in aged transgenic mice expressing the human P301L-Tau mutation. | Bexarotene | microtubule associated protein tau | Homo sapiens |
| 2 | In in vitro studies bexarotene increased the expression of autophagy markers and reduced autophagic flux in neuronal cells expressing P301L-Tau. | Bexarotene | microtubule associated protein tau | Homo sapiens |
| 3 | Bexarotene also restored mitochondrial respiration deficits in P301L-Tau neurons. | Bexarotene | microtubule associated protein tau | Homo sapiens |