Pub. Date : 2016 Nov
PMID : 27622723
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Implication of UGT2B15 Genotype Polymorphism on Postoperative Anxiety Levels in Patients Receiving Lorazepam Premedication. | Lorazepam | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |
| 2 | The UGT2B15 genotype is of importance for the metabolism of lorazepam. | Lorazepam | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |
| 3 | The clinical effect of genetic polymorphisms in UGT2B15 genotype on the treatment of anxiety levels in same-day surgery patients receiving lorazepam, however, is unknown. | Lorazepam | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |
| 4 | Striking was that females with high preoperative anxiety scores and genetically reduced lorazepam glucuronidation (UGT2B15*2 homozygotes) showed more postoperative anxiety reduction than males with the same genotype. | Lorazepam | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |
| 5 | CONCLUSIONS: UGT2B15 genotype contributes to postoperative anxiety reduction after lorazepam premedication. | Lorazepam | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |