Title : Broad Infiltration of Macrophages Leads to a Proinflammatory State in Streptozotocin-Induced Hyperglycemic Mice.

Pub. Date : 2016 Oct 15

PMID : 27619992






1 Functional Relationships(s)
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1 Studies of PMN infiltration during zymosan-induced peritonitis reveal that hyperglycemia enhances PMN recruitment not through inducing a high level of IL-17, which is the case in colitis, but through increasing F4/80+ macrophages in the peritoneal cavity, resulting in elevations of IL-6, IL-1beta, TNF-alpha, and CXCL1 production. Zymosan interleukin 6 Mus musculus