Pub. Date : 2016 Sep 9
PMID : 27618097
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of Folic Acid on Secretases Involved in Abeta Deposition in APP/PS1 Mice. | Folic Acid | amyloid beta (A4) precursor protein | Mus musculus |
| 2 | Previous studies indicated that folate deficiency elevated Abeta deposition in APP/PS1 mice, and this rise was prevented by folic acid. | Folic Acid | amyloid beta (A4) precursor protein | Mus musculus |
| 3 | Previous studies indicated that folate deficiency elevated Abeta deposition in APP/PS1 mice, and this rise was prevented by folic acid. | Folic Acid | amyloid beta (A4) precursor protein | Mus musculus |
| 4 | In the present study, we aimed to investigate whether folic acid could influence the generation of Abeta by regulating alpha-, beta-, and gamma-secretase. | Folic Acid | amyloid beta (A4) precursor protein | Mus musculus |
| 5 | Taken together, the effect of folic acid on Abeta deposition may relate to making APP metabolism through non-amyloidogenic pathway by decreasing beta-secretase and increasing alpha-secretase. | Folic Acid | amyloid beta (A4) precursor protein | Mus musculus |