Title : Ursolic acid sensitized colon cancer cells to chemotherapy under hypoxia by inhibiting MDR1 through HIF-1α.

Pub. Date : 2016 Sep

PMID : 27604859






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Ursolic acid sensitized colon cancer cells to chemotherapy under hypoxia by inhibiting MDR1 through HIF-1alpha. ursolic acid ATP binding cassette subfamily B member 1 Homo sapiens
2 CONCLUSIONS: Ursolic acid exerted chemosensitizing effects in colon cancer cells under hypoxia by inhibiting HIF-1alpha accumulation and the subsequent expression of the MDR1 and VEGF. ursolic acid ATP binding cassette subfamily B member 1 Homo sapiens