Title : Pre-incubation with cyclosporine A potentiates its inhibitory effects on pitavastatin uptake mediated by recombinantly expressed cynomolgus monkey hepatic organic anion transporting polypeptide.

Pub. Date : 2016 Nov

PMID : 27603548






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Pre-incubation with cyclosporine A in vitro before simultaneous incubation with probes has been reported to potentiate its inhibitory effects on recombinant human OATP-mediated probe uptake. Cyclosporine solute carrier organic anion transporter family member 1A2 Homo sapiens
2 In the present study, the effects of cyclosporine A and rifampicin on recombinant cynomolgus monkey OATP-mediated pitavastatin uptake were investigated in pre- and simultaneous incubation systems. Cyclosporine solute carrier organic anion transporter family member 1A2 Homo sapiens