Title : Ibuprofen arginate retains eNOS substrate activity and reverses endothelial dysfunction: implications for the COX-2/ADMA axis.

Pub. Date : 2016 Dec

PMID : 27601438






3 Functional Relationships(s)
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1 Ibuprofen arginate retains eNOS substrate activity and reverses endothelial dysfunction: implications for the COX-2/ADMA axis. Ibuprofen mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 Nonsteroidal antiinflammatory drugs, including ibuprofen, are among the most commonly used medications and produce their antiinflammatory effects by blocking cyclooxygenase (COX)-2. Ibuprofen mitochondrially encoded cytochrome c oxidase II Homo sapiens
3 Ibuprofen arginate functioned similarly to ibuprofen sodium for inhibition of mouse/human COX-2, but only ibuprofen arginate served as a substrate for NOS. Ibuprofen mitochondrially encoded cytochrome c oxidase II Homo sapiens