Title : Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis.

Pub. Date : 2016 Nov

PMID : 27599716






1 Functional Relationships(s)
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1 Inhibition of autophagic clearance of Abeta led to increased ROS levels and aggravating mitochondrial defects, which were blocked by Rapamycin (an mTOR inhibitor). Sirolimus amyloid beta precursor protein Homo sapiens