Title : Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism.

Pub. Date : 1989 Aug

PMID : 2758725






4 Functional Relationships(s)
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1 Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism. Azathioprine thiopurine S-methyltransferase Homo sapiens
2 The enzyme thiopurine methyltransferase (TPMT) plays an important role in azathioprine catabolism. Azathioprine thiopurine S-methyltransferase Homo sapiens
3 The enzyme thiopurine methyltransferase (TPMT) plays an important role in azathioprine catabolism. Azathioprine thiopurine S-methyltransferase Homo sapiens
4 Inherited low TPMT activity appears to be a major risk factor for acute azathioprine-induced myelosuppression. Azathioprine thiopurine S-methyltransferase Homo sapiens