Title : Leucine deprivation inhibits proliferation and induces apoptosis of human breast cancer cells via fatty acid synthase.

Pub. Date : 2016 Sep 27

PMID : 27579768






1 Functional Relationships(s)
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1 Over-expression of FASN or supplementation of palmitic acid (the product of FASN action) blocked the effects of leucine deprivation on cell proliferation and apoptosis in vitro and in vivo. Palmitic Acid fatty acid synthase Homo sapiens