Title : mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1.

Pub. Date : 2016 Sep 1

PMID : 27570073






3 Functional Relationships(s)
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1 mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1. Hexosamines glutamine--fructose-6-phosphate transaminase 1 Homo sapiens
2 We elucidate how mTORC2 modulates a glutamine-requiring biosynthetic pathway, the hexosamine biosynthesis pathway (HBP) via regulation of expression of glutamine:fructose-6-phosphate amidotransferase 1 (GFAT1), the rate-limiting enzyme of the HBP. Hexosamines glutamine--fructose-6-phosphate transaminase 1 Homo sapiens
3 We elucidate how mTORC2 modulates a glutamine-requiring biosynthetic pathway, the hexosamine biosynthesis pathway (HBP) via regulation of expression of glutamine:fructose-6-phosphate amidotransferase 1 (GFAT1), the rate-limiting enzyme of the HBP. Hexosamines glutamine--fructose-6-phosphate transaminase 1 Homo sapiens