Title : TGFβ-induced switch from adipogenic to osteogenic differentiation of human mesenchymal stem cells: identification of drug targets for prevention of fat cell differentiation.

Pub. Date : 2016 Aug 26

PMID : 27562730






1 Functional Relationships(s)
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1 However, when cells are cultured under adipogenic differentiation conditions, which contain cAMP-enhancing agents such as IBMX of PGE2, TGFbeta promotes osteogenic differentiation, while at the same time inhibiting adipogenic differentiation. Dinoprostone transforming growth factor beta 1 Homo sapiens