Title : Evaluation of the Nicotinic Acetylcholine Receptor-Associated Proteome at Baseline and Following Nicotine Exposure in Human and Mouse Cortex.

Pub. Date : 2016 Jul-Aug

PMID : 27559543






1 Functional Relationships(s)
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1 We observed significant effects of nicotine exposure on the beta2*-nAChR-associated proteome in human and mouse cortex, particularly in the abundance of the nAChR subunits themselves, as well as putative interacting proteins that make up core components of neuronal excitability (Na/K ATPase subunits), presynaptic neurotransmitter release (syntaxins, SNAP25, synaptotagmin), and a member of a known nAChR protein chaperone family (14-3-3zeta). Nicotine potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens