Title : 2-Sulfonylpyrimidines: Mild alkylating agents with anticancer activity toward p53-compromised cells.

Pub. Date : 2016 Sep 6

PMID : 27551077






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 PK11007 stabilized p53 in vitro via selective alkylation of two surface-exposed cysteines without compromising its DNA binding activity. Cysteine tumor protein p53 Homo sapiens