Pub. Date : 2016 Sep
PMID : 27549813
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here is reported the development of a novel scoring function that performs remarkably well at identifying the native binding pose of a subset of HSP90 inhibitors containing aminopyrimidine or resorcinol based scaffolds. | 2-aminopyrimidine | heat shock protein 90 alpha family class A member 1 | Homo sapiens |
| 2 | These results indicate that the specific residues considered by PocketScore are determinant to properly model the interaction between HSP90 and its subset of inhibitors containing aminopyrimidine or resorcinol based scaffolds. | 2-aminopyrimidine | heat shock protein 90 alpha family class A member 1 | Homo sapiens |