Pub. Date : 1989 Jul 17
PMID : 2753164
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of phenobarbital on the expression of glutathione S-transferase isoenzymes in cultured rat hepatocytes. | Phenobarbital | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 2 | Cultured adult rat hepatocytes were treated daily with 3.2 mM phenobarbital (PB) in order to study its effect on the expression of cytosolic glutathione S-transferase isoenzymes. | Phenobarbital | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 3 | Cultured adult rat hepatocytes were treated daily with 3.2 mM phenobarbital (PB) in order to study its effect on the expression of cytosolic glutathione S-transferase isoenzymes. | Phenobarbital | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 4 | Glutathione S-transferase (GST) activities, using 1-chloro-2,4-dinitrobenzene and 1,2-dichloro-4-nitrobenzene as substrates, were increased when PB was present in the culture medium. | Phenobarbital | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 5 | Glutathione S-transferase (GST) activities, using 1-chloro-2,4-dinitrobenzene and 1,2-dichloro-4-nitrobenzene as substrates, were increased when PB was present in the culture medium. | Phenobarbital | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 6 | After purification and separation of GST on glutathione Sepharose 6 B and reversed-phase HPLC, respectively, it was observed in vitro that PB caused an increase in the relative amounts of subunits 1, 3 and 7 compared to subunits 2 and 4. | Phenobarbital | hematopoietic prostaglandin D synthase | Rattus norvegicus |