Title : Mechanical activation of angiotensin II type 1 receptors causes actin remodelling and myogenic responsiveness in skeletal muscle arterioles.

Pub. Date : 2016 Dec 1

PMID : 27531064






1 Functional Relationships(s)
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1 KEY POINTS: Candesartan, an inverse agonist of the type 1 angiotensin II receptor (AT1 R), causes a concentration-dependent inhibition of pressure-dependent myogenic tone consistent with previous reports of mechanosensitivity of this G protein-coupled receptor. candesartan angiotensin II receptor, type 1a Rattus norvegicus