Title : Celecoxib and sulindac inhibit TGF-β1-induced epithelial-mesenchymal transition and suppress lung cancer migration and invasion via downregulation of sirtuin 1.

Pub. Date : 2016 Aug 30

PMID : 27528025






1 Functional Relationships(s)
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1 We demonstrated that celecoxib and sulindac were effective in preventing TGF-beta1-induced EMT, as indicated by upregulation of the epithelial marker, E-cadherin, and downregulation of mesenchymal markers and transcription factors. Celecoxib cadherin 1 Homo sapiens