Title : N-Alkyl-Substituted Isatins Enhance P2X7 Receptor-Induced Interleukin-1β Release from Murine Macrophages.

Pub. Date : 2016

PMID : 27524862






2 Functional Relationships(s)
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1 ATP-induced IL-1beta and lactate dehydrogenase (LDH) release were assessed by specific colorimetric assays. Adenosine Triphosphate interleukin 1 beta Mus musculus
2 ATP caused rapid IL-1beta release in a concentration-dependent manner, and this process was completely impaired by the P2X7 antagonist, AZ10606120. Adenosine Triphosphate interleukin 1 beta Mus musculus