Title : Conformational modulation mediated by polyglutamine expansion in CAG repeat expansion disease-associated proteins.

Pub. Date : 2016 Sep 16

PMID : 27520369






1 Functional Relationships(s)
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1 Using these immunoassays, we now report that polyglutamine expansion influences the conformational properties of other polyglutamine disease proteins, exemplified by the androgen receptor (associated with spinal bulbar muscular atrophy) and TATA binding protein (associated with spinocerebellar ataxia 17). polyglutamine androgen receptor Homo sapiens