Pub. Date : 2016 Aug 30
PMID : 27516548
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Enhancement of hERG channel activity by scFv antibody fragments targeted to the PAS domain. | Aminosalicylic Acid | ETS transcription factor ERG | Homo sapiens |
| 2 | We have uncovered a family of positive modulators of hERG that specifically bind to the PAS domain. | Aminosalicylic Acid | ETS transcription factor ERG | Homo sapiens |
| 3 | Overall, these molecules constitute a previously unidentified class of positive modulators and establish that allosteric modulation of hERG channel function through ligand binding to the PAS domain can be attained. | Aminosalicylic Acid | ETS transcription factor ERG | Homo sapiens |