Title : Phosphatidylcholine as a metabolic cue for determining B cell fate and function.

Pub. Date : 2016 Dec

PMID : 27502364






2 Functional Relationships(s)
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1 B cell-specific deletion of CTP:phosphocholine cytidylyltransferase alpha (CCTalpha), the rate-limiting enzyme in the CDP-choline pathway, led to augmented IgM secretion and reduced IgG production, suggesting that PtdCho synthesis is required for germinal center reactions. Phosphatidylcholines phosphate cytidylyltransferase 1, choline, alpha isoform Mus musculus
2 B cell-specific deletion of CTP:phosphocholine cytidylyltransferase alpha (CCTalpha), the rate-limiting enzyme in the CDP-choline pathway, led to augmented IgM secretion and reduced IgG production, suggesting that PtdCho synthesis is required for germinal center reactions. Phosphatidylcholines phosphate cytidylyltransferase 1, choline, alpha isoform Mus musculus