Title : Spatial-Temporal Study of Rab1b Dynamics and Function at the ER-Golgi Interface.

Pub. Date : 2016

PMID : 27500526






1 Functional Relationships(s)
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1 Furthermore, we reveal for first time that Rab1b localization time at ERES depended on GBF1, a Rab1b effector that acts as the guanine nucleotide exchange factor of Arf1, and that Rab1b membrane association/dissociation dynamics at ERES was dependent on the GBF1 membrane association and activity, which strongly suggests that GBF1 activity modulates Rab1b membrane cycling dynamic. Guanine Nucleotides golgi brefeldin A resistant guanine nucleotide exchange factor 1 Homo sapiens