Pub. Date : 2016
PMID : 27494022
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PI-103 and Quercetin Attenuate PI3K-AKT Signaling Pathway in T- Cell Lymphoma Exposed to Hydrogen Peroxide. | Hydrogen Peroxide | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Present study is aimed to analyze PI3K-AKT signaling pathway in H2O2 exposed Dalton"s lymphoma ascite (DLA) cells. | Hydrogen Peroxide | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Exposure of H2O2 (1mM H2O2 for 30min) to DLA cells caused ROS accumulation and resulted in increased phosphorylation of PI3K and downstream proteins PDK1 and AKT (Ser-473 and Thr-308), cell survival factors BAD and ERK1/2, as well as TNFR1. | Hydrogen Peroxide | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | Exposure of H2O2 (1mM H2O2 for 30min) to DLA cells caused ROS accumulation and resulted in increased phosphorylation of PI3K and downstream proteins PDK1 and AKT (Ser-473 and Thr-308), cell survival factors BAD and ERK1/2, as well as TNFR1. | Hydrogen Peroxide | AKT serine/threonine kinase 1 | Homo sapiens |