Title : Docking-based Design of Galantamine Derivatives with Dual-site Binding to Acetylcholinesterase.

Pub. Date : 2016 Jul

PMID : 27492242






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The enzyme acetylcholinesterase is a key target in the treatment of Alzheimer"s disease because of its ability to hydrolyze acetylcholine via the catalytic binding site and to accelerate the aggregation of amyloid-beta peptide via the peripheral anionic site (PAS). Aminosalicylic Acid acetylcholinesterase (Cartwright blood group) Homo sapiens